Understanding cytokinesis: lessons from fission yeast
β Scribed by Pollard, Thomas D.; Wu, Jian-Qiu
- Book ID
- 109959307
- Publisher
- Nature Publishing Group
- Year
- 2010
- Tongue
- English
- Weight
- 671 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1471-0072
- DOI
- 10.1038/nrm2834
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Cytokinesis in the fission yeast, Schizosaccharomyces pombe consists of two distinct but overlapping events: the assembly and constriction of a cytokinetic actomyosin ring (CAR) and the formation of a cross wall or septum. These two processes must be spatially and temporally coordinated both with ea
Calcineurin (protein phosphatase 2B), the only serine/threonine phosphatase under the control of Ca^2+^/calmodulin, is an important mediator in signal transmission, connecting the Ca^2+^βdependent signalling to a wide variety of cellular responses. Furthermore, calcineurin is specifically inhibited