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Uncoupling protein UCP3 up-regulation during cardioplegia-induced ischemia in the human heart

✍ Scribed by López-Bernardo, E.; Anedda, A.; Acosta-Iborra, B.; Vaca, C.; Salamanca, J.; Bustamante, J.; Landázuri, M.O.; Cadenas, S.

Book ID: 122115239
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 56 KB
Volume: 1817
Category: Article
ISSN: 0005-2728
DOI: 10.1016/j.bbabio.2012.06.123

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## Abstract Hyperglycemia is the hallmark of diabetes mellitus. Poor glycemic control is correlated with increased cardiovascular morbidity and mortality. High glucose can trigger endothelial cell apoptosis by de‐activation of endothelial nitric oxide synthase (eNOS). eNOS was recently demonstrated