✦ LIBER ✦

Uncoupling Protein-2 Negatively Regulates Insulin Secretion and Is a Major Link between Obesity, β Cell Dysfunction, and Type 2 Diabetes

✍ Scribed by Chen-Yu Zhang; György Baffy; Pascale Perret; Stefan Krauss; Odile Peroni; Danica Grujic; Thilo Hagen; Antonio J. Vidal-Puig; Olivier Boss; Young-Bum Kim; Xin Xiao Zheng; Michael B. Wheeler; Gerald I. Shulman; Catherine B. Chan; Bradford B. Lowell

Book ID: 117268768
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 354 KB
Volume: 105
Category: Article
ISSN: 0092-8674
DOI: 10.1016/s0092-8674(01)00378-6

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Fatty acid-induced mitochondrial uncoupl

Fatty acid-induced mitochondrial uncoupling in adipocytes as a key protective factor against insulin resistance and beta cell dysfunction: a new concept in the pathogenesis of obesity-associated type 2 diabetes mellitus

✍ J. A. Maassen; J. A. Romijn; R. J. Heine 📂 Article 📅 2007 🏛 Springer 🌐 English ⚖ 152 KB

Up-regulation of PPARγ, heat shock prote

Up-regulation of PPARγ, heat shock protein-27 and -72 by naringin attenuates insulin resistance, β-cell dysfunction, hepatic steatosis and kidney damage in a rat model of type 2 diabetes

✍ Kumar Sharma, Ashok; Bharti, Saurabh; Ojha, Shreesh; Bhatia, Jagriti; Kumar, Nar 📂 Article 📅 2011 🏛 Cambridge University Press 🌐 English ⚖ 568 KB

Early-onset type 2 diabetes in obese whi

Early-onset type 2 diabetes in obese white subjects is characterised by a marked defect in beta cell insulin secretion, severe insulin resistance and a lack of response to aerobic exercise training

✍ N. Burns; F. M. Finucane; M. Hatunic; M. Gilman; M. Murphy; D. Gasparro; A. Mari 📂 Article 📅 2007 🏛 Springer 🌐 English ⚖ 186 KB