Uncoupling of biliary lipid from bile acid secretion by formyl- methionyl-leucyl-phenylalanine in the rat

✍ Scribed by K Mizuno; M Hoshino; T Hayakawa; H Yamada; T Nakazawa; T Inagaki; T Takeuchi; M Kunimatsu

• Publisher: John Wiley and Sons
• Year: 1996
• Tongue: English
• Weight: 245 KB
• Volume: 24
• Category: Article
• ISSN: 0270-9139
• DOI: 10.1002/hep.510240540

✦ Synopsis

tubing (Clay Adams, Parsippany, NJ). The pancreatic-duodenal branch of the portal vein was then ligated, and the portal vein was cannulated using a 14-gauge Teflon intravenous catheter (Critikon Abbreviations: fMLP, N-formyl-methionyl-leucyl-phenylalanine; HRP, horseradish per-Inc., Tampa, FL). The liver was perfused immediately at a constant oxidase; TCA, sodium taurocholate. flow rate of 20 mL/min with oxygenated (95% O 2 /5% CO 2