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Uncoupling JAK3 activation induces apoptosis in human lymphoid cancer cells via regulating critical survival pathways

✍ Scribed by Zsuzsanna S. Nagy; Jeremy A. Ross; Georgialina Rodriguez; Julia Bader; Jonathan Dimmock; Robert A. Kirken


Book ID
113621920
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
634 KB
Volume
584
Category
Article
ISSN
0014-5793

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## Abstract We observed that treatment of prostate cancer cells for 24 h with magnolol, a phenolic component extracted from the root and stem bark of the oriental herb __Magnolia officinalis__, induced apoptotic cell death in a dose‐ and time‐dependent manner. A sustained inhibition of the major su