A method for the separation and detection of bile acid 3-glucuronides by liquid chromatography (LC)/ electrospray ionization (ESI)-mass spectrometry (MS) has been developed. On the ESI mode, glucuronides were characterized by an intense pseudo-molecular ion [M-HI-with a doubly charged ion [M-2HI2-,
✦ LIBER ✦
Unconjugated faecal bile acids in familial adenomatous polyposis analysed by gas-liquid chromatography and mass spectrometry
✍ Scribed by G. M. Barker; S. Radley; A. Davis; C. H. E. Imray; K. D. R. Setchell; N. O'Connell; I. A. Donovan; M. R. B. Keighley; Mr J. P. Neoptolemos
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 443 KB
- Volume
- 81
- Category
- Article
- ISSN
- 0007-1323
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Solid-phase extraction and group separation by anion exchange chromatography were combined with capillary column liquid chromatography-mass spectrometry (LC/MS) to permit a thorough characterization of bile acids and intact conjugates of bile alcohols in human urine. Groups of compounds were separat