✦ LIBER ✦

Unclassified sclerosing bone dysplasia with osteopathia striata, cranial sclerosis, metaphyseal undermodeling, and bone fragility

✍ Scribed by Nakamura, Kozo; Nakada, Yutaka; Nakada, Daisuke

Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 40 KB
Volume: 76
Category: Article
ISSN: 0148-7299
DOI: 10.1002/(sici)1096-8628(19980413)76:5<389::aid-ajmg5>3.0.co;2-i

No coin nor oath required. For personal study only.

✦ Synopsis

Sclerosing bone dysplasias are diagnosed on the basis of a characteristic pattern of osteosclerosis and clinical manifestations; in many of them, cause and pathogenesis are still unknown. A 33-year-old man had five fractures of the humerus, tibiae, and femur as a result of mild traumatic incidents that occurred between the ages of 18 and 33 years as well as a remnant of rib fractures without apparent trauma on radiographs. His height was 158 cm (-2.2 SD). Radiographic evaluation showed cranial sclerosis, longitudinal striations in the metaphyses of the femur and tibia, fan-like striation in the ilium, metaphyseal widening in the femur and tibia, and sclerosis of the ribs. The blood chemistry findings, including serum calcium, phosphorus, and alkaline phosphatase, were normal. Biopsy from the ilium showed thick trabeculae composed of woven bone. The coexistence of osteopathia striata, cranial sclerosis, metaphyseal undermodeling, and bone fragility has not been recognized previously. Our case appears to represent a new form of sclerosing bone dysplasia.

📜 SIMILAR VOLUMES

Gracile bone dysplasia

✍ Thomas, Janet A.; Rimoin, David L.; Lachman, Ralph S.; Wilcox, William R. 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 52 KB 👁 2 views

Gracile bones are a frequent abnormality associated with fetal hypokinesia of any cause. With the exception of thin, undermineralized bones, the chondro-osseous structure is usually normal in these cases. We present a lethal skeletal dysplasia comprising minor anomalies, central nervous system abnor

Multiple Sclerosis

✍ Marie-Annick Courtier 📂 Fiction 📅 2009 🏛 Hatherleigh Press 🌐 en-US ⚖ 315 KB 👁 2 views

Can practicing a healthy lifestyle, which includes a healthy diet, decrease Multiple Sclerosis symptoms' In the U.S. alone, approximately 400,000 people suffer from Multiple Sclerosis (MS). MS is an autoimmune disease that affects the central nervous system. There are a variety of symptoms of MS, an

Micromelic dwarfism with cone epiphyses,

Micromelic dwarfism with cone epiphyses, metaphyseal dysplasia, and vertebral segmentation defects

✍ Fryns, Jean-Pierre; Lorenzetti, Maria-Elena; Maroteaux, Pierre; Van den Berghe, 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 14 KB 👁 2 views

We present the clinical and radiological findings in a newborn male with severe micromelic dwarfism, short neck, short and narrow upper thorax, and brachydactyly. At the age of 1 year mental development is slightly retarded. The X-ray findings of severe vertebral segmentation defects and a generaliz

Misty Bane - 04 Broomsticks and Bones

✍ Misty Bane 📂 Fiction 📅 2019 🌐 English ⚖ 80 KB 👁 2 views

Fragile Bond

✍ Rhi Etzweiler 📂 Fiction 📅 2013 🏛 Riptide Publishing 🌐 English ⚖ 170 KB 👁 2 views

Sniper Sergeant Marc Staille and his trusty rifle, Mat, are on bodyguard duty at a mining operation on a backwater planet. The resource-rich valley is crawling with tawnies, the native dirt-colored predators. Huge things that hunt in packs and kill as well with tooth and claw as Marc ever has with M

Fragile Bond

✍ Rhi Etzweiler 📂 Fiction 📅 2013 🏛 Riptide Publishing 🌐 English ⚖ 170 KB 👁 2 views