Hepatitis C virus (HCV) is a positive-polarity, single-stranded RNA virus, distantly related to the pestivirus and flavivirus genera. These viruses replicate through the formation of a minusstrand RNA intermediate, which encodes the positive-strand genome, which is subsequently encapsidated, envelop
β¦ LIBER β¦
Unchanged serum viral load and liver function during tocilizumab treatment in a patient with rheumatoid arthritis and hepatitis C virus infection
β Scribed by Nagashima, Takao; Maruyama, Akihito; Kamata, Yasuyuki; Minota, Seiji
- Book ID
- 113029045
- Publisher
- Springer
- Year
- 2011
- Tongue
- English
- Weight
- 112 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0172-8172
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Reactive systemic AA amyloidosis is a severe complication of rheumatoid arthritis (RA), occurring in 2-5% of RA patients (1). Infliximab, a monoclonal antibody against tumor necrosis factor β£ (TNFβ£), is successfully used in the treatment of RA (2). TNFβ£ plays a key role in inducing the synthesis of