Uncatalyzed Three-Component Synthesis of α-Hydrazido Phosphonates
✍ Scribed by Raquel P. Herrera; David Roca-López; Gloria Navarro-Moros
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 132 KB
- Volume
- 2010
- Category
- Article
- ISSN
- 1434-193X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract α‐Hydroxylamino phosphonates are synthesised in a one‐pot operation by three‐component coupling reactions of aldehydes, hydroxylamines and diethyl phosphite using 1‐butyl‐3‐methylimidazolium tetrafluoroborate ([bmim]BF~4~) or 1‐butyl‐3‐methylimidazolium hexafluorophosphate ([bmim]PF~6~)
## Abstract Uncatalyzed one‐pot, three‐component reactions of aldehydes, chiral α‐methylamines, and dimethyl phosphite under solvent‐free conditions were used for the diastereoselective synthesis of α‐amino phosphonates. The reactions proceeded with extremely high efficiency under mild conditions a