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Unbalanced translocations of 20q in AML and MDS often involve interstitial rather than terminal deletions of 20q

✍ Scribed by Ruth N. MacKinnon; Hendrika M. Duivenvoorden; Lynda J. Campbell


Book ID
116332563
Publisher
Elsevier
Year
2011
Tongue
English
Weight
413 KB
Volume
204
Category
Article
ISSN
2210-7762

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## Abstract Multiple myeloma (MM) and monoclonal gammopathy of undetermined significance (MGUS) are characterized cytogenetically by 14q32 rearrangements, βˆ’13/13qβˆ’, and various trisomies. Occasionally, karyotypic patterns characteristic of myelodysplastic syndrome (MDS)/acute myeloid leukemia (AML)