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Unanchoring integrins in focal adhesions

✍ Scribed by Ivaska, Johanna


Book ID
120067408
Publisher
Nature Publishing Group
Year
2012
Tongue
English
Weight
176 KB
Volume
14
Category
Article
ISSN
1465-7392

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Integrins interact with focal adhesions
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Integrin signaling involves oligomerization and a transmembrane conformational change induced by receptor occupancy. Previous work has shown that subsets of focal adhesion-associated proteins are recruited to integrins as a result of clustering, ligand binding, or both. However, it is unclear whethe