Unambiguous NMR spectral assignments of salvinorin A

✍ Scribed by José-Luis Giner; David J. Kiemle; Lukasz Kutrzeba; Jordan Zjawiony

• Book ID: 102526682
• Publisher: John Wiley and Sons
• Year: 2007
• Tongue: English
• Weight: 113 KB
• Volume: 45
• Category: Article
• ISSN: 0749-1581
• DOI: 10.1002/mrc.1972

✦ Synopsis

Abstract

The complete assignments of the ^1^H and ^13^C NMR spectra of the hallucinogenic neoclerodane diterpenoid salvinorin A were determined in three different NMR solvents using HSQC, HMBC and COSY. Solvent systems are described that allow the resolution of all ^1^H signals. Virtual coupling was observed for the protons at C‐2, C‐3 and C‐4 in the 600 MHz ^1^H spectrum in CDCl~3~. The complete assignments of the ^1^H and ^13^C NMR spectra of salvinorin B are also reported. Copyright © 2007 John Wiley & Sons, Ltd.