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Ultraviolet B-induced activation of melanocytes is mediated through interferon-gamma secreted by macrophages

✍ Scribed by M. Raza Zaidi; Edward De Fabo; Sean Davis; Cari Graff-Cherry; Teresa Hawley; Lionel Feigenbaum; Elaine Fuchs; Thomas Hornyak; Heinz Arnheiter; Giorgio Trinchieri; Frances Noonan; Paul Meltzer; Glenn Merlino

Book ID: 116398958
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 45 KB
Volume: 48
Category: Article
ISSN: 1043-4666
DOI: 10.1016/j.cyto.2009.07.151

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## Abstract A proinflammatory cytokine IFN‐γ stimulates microglia in the injured brain; however, signaling pathways for IFN‐γ‐mediated microglia activation are not well characterized. In the present study, a protein kinase C (PKC) activator phorbol 12‐myristate 13‐acetate (PMA) acts in concert with