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Ultraviolet and attenuated total reflectance infrared spectra of chlorpromazine metabolites

✍ Scribed by R. J. Warren; W. E. Thompson; J. E. Zarembo; I. B. Eisdorfer

Publisher
John Wiley and Sons
Year
1967
Tongue
English
Weight
394 KB
Volume
56
Category
Article
ISSN
0022-3549

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✦ Synopsis

Ultraviolet absorption and attenuated total reflectance infrared spectra of chlorpromazine and 14 possible metabolites have been recorded and analyzed. Structural correlations of the absorption bands are presented and discussed. This collection provides a positive means of identifying chlorpromazine metabolites extracted from body fluids and tissues and separated by chromatographic techniques. Spectral identification can be made on microgram samples.

DENTIPICATION of the metabolites of chlor-

RESULTS AND DISCUSSION

Infrared Spectra (ATR)-Although it is possible that transmission spectra and ATR spectra of

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