Pathogenesis of malformations in a roden
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Dehart, D. B.; Lanoue, L.; Tint, G. S.; Sulik, K. K.
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Article
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1997
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John Wiley and Sons
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English
⚖ 549 KB
The fact that Smith-Lemli-Opitz syndrome (SLOS), a syndrome comprising major malformations involving a number of organ systems, results from an abnormality in cholesterol biosynthesis, was discovered only recently. Utilizing a drug (BM 15.766) to inhibit the same step in cholesterol biosynthesis as