There are two major types of artificial heart valves in use, namely mechanical valves and bioprosthetic valves. Mechanical valves last longer but require the recipient to undergo long-term anticoagulant therapy. Bioprosthetic valves are more biocompatible than the mechanical valves and long-term ant
Ultrastructural substrates of porcine bioprosthetic valve dysfunction
β Scribed by M. Valente; E. Arbustini; G. Miotti Scapin; G. Thiene
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- English
- Weight
- 89 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0304-3991
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## Abstract Explanted porcine bioprosthetic valves have a thinned spongiosa, partially because of an overall loss of glycosaminoglycans (GAGs). We measured the concentrations of specific GAG classes in explanted bioprosthetic valves (n = 14, implanted 12.0 Β± 4.7 years) compared with glutaraldehydeβ
In this study, we examined separately calcification of cusps (C) and associated aortic wall (AW) of 38 (13 aortic and 25 mitral) porcine bioprosthetic heart valves explanted from 37 patients (ages 25-80 years, mean 59) for structural dysfunction, following 54-210 months (mean 125 months aortic, 119