Ultrastructural Differences of hepatocytes in iron overload
โ Scribed by J.W. Sindram; M.I. Cleton; L.H.P.M. Rademakers; J.J.M. Marx
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- English
- Weight
- 173 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0304-3991
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
After a single subcutaneous dose of iron-dextran (600 mg of ironkg), iron overload developed in CS7BL/lOScSn mice. At 4,24 and 78 wk liver nonheme iron concentrations were 67-, 42-and 21-fold higher than controls, respectively. Much of the iron was in macrophages, but hepatocytes were also strongly
Ferritin-like particles were observed in bile canaliculi of patients with iron overload. These particles have been further investigated by: (1) a staining method enhancing the size and contrast of ferritin protein, and (2) electron probe microanalysis detecting the presence of the elements iron and