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ULTRASOUND SCREENING FOR SPINA BIFIDA: CRANIAL AND CEREBELLAR SIGNS

✍ Scribed by Nicolaides, K.H.; Gabbe, S.G.; Campbell, S.; Guidetti, R.


Book ID
122401939
Publisher
The Lancet
Year
1986
Tongue
English
Weight
605 KB
Volume
328
Category
Article
ISSN
0140-6736

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## Abstract **BACKGROUND:**__PAX3__ plays an important role in mammalian embryonic development. Known mutations in __PAX3__ are etiologically associated with Waardenburg syndrome and syndromic neural tube defects (NTDs). Mutations in the murine homologue, __pax3__, are responsible for the phenotype