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Ultrasound-mediated gene delivery: Kinetics of plasmid internalization and gene expression

✍ Scribed by Sophie Mehier-Humbert; Thierry Bettinger; Feng Yan; Richard H. Guy

Book ID
113690848
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
197 KB
Volume
104
Category
Article
ISSN
0168-3659

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Background Injection of DNA encoding exogenic proteins into muscle tissue combined with electroporation often results in a transient increase of the encoded protein concentration in the muscle and the blood. The reduction is normally due to an immune response against the exogenic protein but other f