𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Ultrasound-Induced Disruption of Amphiphilic Block Copolymer Micelles

✍ Scribed by Juan Xuan; Maxime Pelletier; Hesheng Xia; Yue Zhao

Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
892 KB
Volume
212
Category
Article
ISSN
1022-1352

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Ultrasound‐induced disruption of PEO‐b‐PTHPMA, PEO‐b‐PIBMA, PEO‐b‐PTHFEMA, and PEO‐b‐PMMA block copolymer micelles in aqueous solution was investigated. Fluorescence change of loaded NR, DLS, IR, AFM, and SEM show that those micelles could be disrupted differently by 1.1 MHz high‐intensity focused ultrasound beams. The micelles of PEO‐b‐PIBMA and PEO‐b‐PTHPMA appear to be more sensitive to ultrasound irradiation, resulting in a more severe micellar disruption, and IR spectra show evidence of ultrasound‐induced chemical reactions, most likely hydrolysis. PEO‐b‐PMMA appear to resist HIFU irradiation better, and IR analysis found no evidence of chemical reactions. This study provides new evidence for the prospect of ultrasound‐responsive BCP micelles for controlled delivery applications. magnified image

📜 SIMILAR VOLUMES

Amphiphilic Block Copolymer Micelles: Ne
Amphiphilic Block Copolymer Micelles: New Dispersant for Single Wall Carbon Nanotubes
✍ Hye-in Shin; Byung Gil Min; Wonyong Jeong; Cheolmin Park 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 362 KB

## Abstract **Summary:** This manuscript describes a new simple method to disperse single wall carbon nanotubes (SWNTs) in various organic solvents. The method is based on using amphiphilic block copolymer micelles as a dispersant. We have found that the stabilization of SWNTs by block copolymer mi

Micellization and the Surface Hydrophobi
Micellization and the Surface Hydrophobicity of Amphiphilic Poly(vinylphenol)-block-Polystyrene Block Copolymers
✍ Pao-Hsaing Tung; Shiao-Wei Kuo; Shih-Chien Chan; Chih-Hao Hsu; Chih-Feng Wang; F 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 424 KB

## Abstract The self‐assembly of PVPh‐__b__‐PS in different solvents was studied. Upon replacing toluene by THF as the solvent, the morphology of the resulting aggregates change from core‐shell spheres, rod‐like micelles and vesicles to onion‐like aggregates. With increasing block copolymer concent

SANS Study of Coated Block Copolymer Mic
SANS Study of Coated Block Copolymer Micelles
✍ Josef Pleštil; Jaroslav Kříž; Čestmír Koňák; Herman Pospíšil; Petr Kadlec; Zdeňk 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 193 KB

## Abstract **Summary:** Multishell particles were prepared by __γ__‐radiation‐induced polymerization of methyl methacrylate (MMA) in polystyrene‐block‐poly(methacrylic acid) (PS‐__b__‐PMA) aqueous micellar solution and their structure was studied by small‐angle neutron scattering (SANS). Before po

Novel Amphiphilic Styrene-Based Block Co
Novel Amphiphilic Styrene-Based Block Copolymers for Induced Surface Reconstruction
✍ Lutz Funk; Martin Brehmer; Rudolf Zentel; Huiman Kang; Kookheon Char 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 355 KB

## Abstract This paper describes the synthesis of amphiphilic block copolymers by living radical polymerization (NMP) of new styrene‐like monomers. The polar monomers (ethylene oxide side chains and free hydroxyl‐ or amino‐groups after deprotection) were polymerized in a “protected form” to adjust