✦ LIBER ✦
Ultrasound in organic synthesis 15. Radical cyclisation of o-allyl benzamides via the sonochemically generated radical anions
✍ Scribed by Jacques Einhorn; Cathy Einhorn; Jean-Louis Luche
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- French
- Weight
- 142 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
By reaction with lithium metal in THF under sonochemical activation, o-ally1 tertiary benzamides are easily cyclised to 2-methyl-indanone. Yields strongly depend on the substitution pattern of the nitrogen atom. Synthetic methods based on carbon-carbon bond formation by radical pathways are of increasing