✦ LIBER ✦
Ultrasonic relaxation associated with proton transfer and aggregation in aqueous solution of some antihistamine drugs containing a maleate counterion
✍ Scribed by William J. Gettins; Richard C. Greenwood; Evan Wyn-Jones
- Publisher
- Elsevier Science
- Year
- 1981
- Weight
- 365 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0378-4487
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✦ Synopsis
Two relaxation processes have been observed in aqueous solution of antihistamines containing the maleate counterion.
The slower relaxation is associated with proton transfer between the maleate counterion and the antihistamine base and rate constants for this process have been estimated. The faster of the two processes is associated with the aggregation of the antihistamine bases and is non-micellar.