Ultrafiltration Membranes Composed of Highly Cross-Linked Cationic Polymer Gel: the Network Structure and Superior Separation Performance
✍ Scribed by Qifeng Wang; Sadaki Samitsu; Izumi Ichinose
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 482 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0935-9648
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✦ Synopsis
Hydrophilic polymer gels are attractive materials for a wide range of applications in the life sciences and bioengineering. The gels are environmentally responsive and have high potential in numerous applications such as drug delivery, sensors, actuators, absorbents, and scaffolds. The transport of ions and molecules through hydrated polymer gels has been investigated by many researchers, as has the bioaffi nity and mechanical properties of these gels. Poly(4-vinylpyridine) (P4VP) forms typical hydrated polymer gels. This polymer is readily cross-linked with alkyl dihalide at room temperature via quaternization of the pyridine groups. Cross-linkers of various size and shape can be used, resulting in P4VP gels with diverse structures and properties. Thin fi lms made of cross-linked poly(vinylpyridine) gels have been widely investigated as a means of applying stimuli-evoked optical, impedance, and volume changes to sensors and biodevices. P4VP has intrinsic selective permeability for gases, and the network structures of these gels can be controlled by controlling the extent of cross-linking. Therefore, this polymer has also been studied for its utility in gas separation, desalination, and pervaporation membranes. However, like most polymer gels, P4VP gels are mechanically weak, and the gel membranes, which are generally supported on a microfi ltration membrane, have thicknesses of a few to several tens of micrometers. In order to be practical, the separation layer needs to be as thin as possible to realize high liquid/gas fl uxes, which requires that the gels are mechanically stable. We here report ultrafi ltration membranes with thicknesses of several tens to hundreds of nanometers, prepared from P4VP gels by means of a two-step cross-linking of the polymer chains. The detailed structure of the polymer network was characterized using spectroscopic techniques and permeation and rejection experiments. Furthermore, the gel membranes were demonstrated to distinguish between water-soluble proteins of different molecular masses.
The methodology for preparing ultrathin ultrafi ltration membranes of the cross-linked P4VP gel is shown in COMMUNICATION