✦ LIBER ✦

Ultrafast imaging of tissue ablation by a XeCl excimer laser in saline

✍ Scribed by Dr. Melitta B. Preisack; Walter Neu; Ralf Nyga; Manfred Wehrmann; Karl K. Haase; Karl R. Karsch

Publisher: John Wiley and Sons
Year: 1992
Tongue: English
Weight: 810 KB
Volume: 12
Category: Article
ISSN: 0196-8092
DOI: 10.1002/lsm.1900120511

No coin nor oath required. For personal study only.

✦ Synopsis

To determine the temporal evolution of laser induced tissue ablation, arterial wall specimens with either hard calcified or fatty plaques and normal tissue were irradiated in a 0.9% saline solution using a XeCl excimer laser (wavelength 308 nm, energy fluence 7 J/cm2, pulse width 30 ns) through a 600 pm fused silica fiber pointing perpendicular either at a 0.5 mm distance or in direct contact to the vascular surface. Radiation of a pulsed dye laser (wavelength 580 nm) was used to illuminate the tissue surface. The ablation process and the arising bubble above the tissue surface were recorded with a CCD camera attached to a computer based image-processing system. Spherical cavitation bubbles and small tissue particles emerging from the irradiated area have been recorded. The volume of this bubble increased faster for calcified plaques than for normal tissue.

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