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Ulcerative Colitis-Associated Colorectal Cancer is Frequently Associated with the Microsatellite Instability Pathway

✍ Scribed by Ichiro Fujiwara; Masakazu Yashiro; Naoshi Kubo; Kiyoshi Maeda; Kosei Hirakawa

Book ID
106323085
Publisher
Springer
Year
2008
Tongue
English
Weight
151 KB
Volume
51
Category
Article
ISSN
0012-3706

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## Abstract It is generally accepted that both dysfunction of the Wnt signaling pathway, including mutations in the adenomatous polyposis coli (__APC__) and β‐catenin genes, and genetic instability play important roles in colorectal carcinogenesis. However, alteration of the components in the Wnt s