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UGT1A1 gene polymorphism as a potential factor inducing iron overload in the pathogenesis of type 1 hereditary hemochromatosis

✍ Scribed by Tomasz Romanowski; Katarzyna Sikorska; Krzysztof Piotr Bielawski


Book ID
118088112
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
290 KB
Volume
39
Category
Article
ISSN
1386-6346

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Hereditary hemochromatosis (HH) is characterized by increased intestinal iron absorption that may result in iron overload. Although phlebotomy is widely practiced, it is poorly tolerated or contraindicated in patients with anemias, severe heart disease, or poor venous access, and compliance can vary