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UDP-N-acetylglucosamine:α-6-d-mannoside β1,6 N-acetylglucosaminyltransferase V (Mgat5) deficient mice

✍ Scribed by James W. Dennis; Judy Pawling; Pam Cheung; Emily Partridge; Michael Demetriou


Book ID
117481066
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
322 KB
Volume
1573
Category
Article
ISSN
0304-4165

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Previous reports have suggested that changes in oligosaccharide structures, especially ␤1-6 branching in N-glycans, which are biosynthesized by UDP-N-acetylglucosamine:␣ mannoside ␤1,6 N-acetylglucosaminyltransferase (GnT-V), are linked to tumor metastasis and invasion. In the present study, we inve