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UDP-glucuronosyltransferase 1A6 overexpression in breast cancer cells resistant to methotrexate

✍ Scribed by M. Cristina de Almagro; Elisabet Selga; Rémi Thibaut; Cinta Porte; Véronique Noé; Carlos J. Ciudad

Book ID
113489374
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
707 KB
Volume
81
Category
Article
ISSN
0006-2952

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## Abstract Cripto‐1 (CR‐1) is an epidermal growth factor (EGF)‐CFC protein that has been shown to signal through nodal/Alk‐4, PI3K/Akt, and/or ras/raf/MEK/MAPK pathways in mammalian cells, and that is frequently expressed in human primary breast carcinomas. In the present study, the human estrogen