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UCP2 protects hypothalamic cells from TNF-α-induced damage

✍ Scribed by Giovanna R. Degasperi; Talita Romanatto; Raphael G.P. Denis; Eliana P. Araújo; Juliana C. Moraes; Natália M. Inada; Aníbal E. Vercesi; Lício A. Velloso

Book ID
113620951
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
796 KB
Volume
582
Category
Article
ISSN
0014-5793

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## Abstract p38 MAP kinases (p38) and c‐Jun N‐terminal protein kinases (JNK) have been associated with TNF‐α‐induced apoptosis. However, recent studies indicate that an early but brief activation of JNK and/or p38 may actually protect some cells from TNF‐α‐induced apoptosis. Whether the activation