FAK regulates tyrosine phosphorylation o
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Shyamali Roy; Paul J. Ruest; Steven K. Hanks
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Article
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2002
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John Wiley and Sons
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English
β 337 KB
## Abstract FAK (focal adhesion kinase) is a nonreceptor proteinβtyrosine kinase activated by tyrosine phosphorylation following integrinβmediated cell adhesion. Oncogenic Src promotes enhanced and deregulated FAK tyrosine phosphorylation which has been proposed to contribute to altered cell growth