Tyrosine phosphorylation and activation of the tec family kinase member emt/itk/tsk following CD28 and CD3 crosslinking

Lipid rafts as the signaling scaffold fo

Lipid rafts as the signaling scaffold for NK cell activation: tyrosine phosphorylation and association of LAT with phosphatidylinositol 3-kinase and phospholipase C-γ following CD2 stimulation

✍ Hiroshi Inoue; Michihiko Miyaji; Atsushi Kosugi; Masakazu Nagafuku; Toshiro Okaz 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 331 KB 👁 2 views

Natural killer (NK) cells participate in both innate and adaptive immunity through the prompt secretion of cytokines and ability to lyse virally infected cells or tumor cells. Although it has been well understood that lipid rafts (rafts) and a raft-associated linker for activation of T cells (LAT) p