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Tyrosine phosphatase SHP-2 is a mediator of activity-dependent neuronal excitotoxicity

✍ Scribed by Rusanescu, Gabriel; Yang, Wentian; Bai, Ailin; Neel, Benjamin G; Feig, Larry A


Book ID
110030918
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
263 KB
Volume
24
Category
Article
ISSN
0261-4189

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An osteoclastic protein-tyrosine phospha
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## Abstract This study tested the hypothesis that an osteoclastic protein‐tyrosine phosphatase, PTP‐oc, enhances osteoclast activity through c‐Src activation. The effects of several resorption activators and inhibitors on PTP‐oc expression, resorption activity, and c‐Src activation were determined