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Tyrosine phosphatase inhibitor prevents peroxynitrite-induced cell death of human neuroblastoma SH-SY5Y cells

✍ Scribed by Makio Saeki; Tomohiko Kanesaki; Takashi Yamada; Yasuhiro Ooi; Sadaaki Maeda

Book ID
117365202
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
116 KB
Volume
31
Category
Article
ISSN
0168-0102

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Vanadate protects human neuroblastoma SH
Vanadate protects human neuroblastoma SH-SY5Y cells against peroxynitrite-induced cell death
✍ Makio Saeki; Sadaaki Maeda; Yoshinori Kamisaki πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 149 KB

## Abstract We investigated the effect of vanadate, a tyrosine phosphatase inhibitor, on cell death induced by peroxynitrite in human neuroblastoma SH‐SY5Y cells. Vanadate prevented cell death induced by 3‐morpholinosydnonimine (SIN‐1), a peroxynitrite donor; whereas SIN‐1‐induced cell death was no