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Tyrosine kinase inhibitors in treating soft tissue sarcomas: sunitinib in non-GIST sarcomas

โœ Scribed by Blanca Homet Moreno; Elena Garralda Cabanas; Ricardo Hitt

Book ID
107597676
Publisher
Springer Milan
Year
2010
Tongue
Spanish
Weight
142 KB
Volume
12
Category
Article
ISSN
1699-048X

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Inactivation of the TSG101 gene was recently shown to induce malignant transformation of NIH/3T3 fibroblasts. Abnormal TSG101 transcription profiles were observed in various human cancers, and large intragenic deletions of the TSG101 gene were reported for a series of human breast cancer specimens,