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Tyrosine kinase inhibitors in cancer therapy

✍ Scribed by Srinivasan Madhusudan; Trivadi S. Ganesan

Book ID
108095259
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
518 KB
Volume
37
Category
Article
ISSN
0009-9120

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## Abstract ## BACKGROUND: Somatic mutations in the epidermal growth factor receptor (EGFR) kinase domain are associated with sensitivity to EGFR‐tyrosine kinase inhibitors (EGFR‐TKI) in patients with nonsmall cell lung cancer (NSCLC). ## METHODS: The authors tested the possibility that nucleoti