## Abstract Germ line gainβofβfunction mutations in several members of the RAS/ERK pathway, including __PTPN11__, __KRAS__, and __RAF1,__ cause the autosomal dominant genetic disorder Noonan Syndrome (NS). NS patients are at increased risk of leukemia/myeloproliferative disease and possibly some so
Tyrosine kinase activating mutations in human malignancies: Implications for diagnostic pathology
β Scribed by Joseph A. Holden; Carlynn Willmore-Payne; Lester J. Layfield
- Book ID
- 113956571
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 951 KB
- Volume
- 85
- Category
- Article
- ISSN
- 0014-4800
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