## Abstract Severe acute respiratory syndrome (SARS) is an emerging infectious disease. Its etiological agent has been convincingly identified as a new member of family Coronaviridae (SARSβCoV). It causes serious damage to the respiratory system yet the mechanism is not clear. Infectionβinduced apo
Tyrosine dephosphorylation of STAT3 in SARS coronavirus-infected Vero E6 cells
β Scribed by Tetsuya Mizutani; Shuetsu Fukushi; Masaaki Murakami; Toshio Hirano; Masayuki Saijo; Ichiro Kurane; Shigeru Morikawa
- Book ID
- 116464973
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 242 KB
- Volume
- 577
- Category
- Article
- ISSN
- 0014-5793
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## Abstract The aim of the study was to establish the life cycle of severe acute respiratory syndromeβassociated coronavirus (SARS CoV) in host cells and determine the pathogenesis of SARS. Vero E6 cells (African green monkey kidney cells) were inoculated with SARS coronavirus for 3, 7, 24, 48, and
## Abstract An isolate from a patient in the recent severe acute respiratory syndrome (SARS) outbreak in Singapore was used to infect Vero E6 cells. This study concentrated on the first 30 min of infection. It was discovered that the SARS coronavirus attached, entered, and uncoated the nucleocapsid