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Tyrosine-1290 of tetanus neurotoxin plays a key role in its binding to gangliosides and functional binding to neurones

โœ Scribed by J.Mark Sutton; Oliver Chow-Worn; Lindsey Spaven; Nigel J Silman; Bassam Hallis; Clifford C Shone


Book ID
117102841
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
276 KB
Volume
493
Category
Article
ISSN
0014-5793

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## Abstract P2Pโ€R is the alternately spliced product of the P2Pโ€R/PACT gene in that P2Pโ€R lacks one exon encoding 34 amino acids. The 250 kDa P2Pโ€R protein is the predominate product expressed in multiple murine cell lines. It is a highly basic protein that contains multiple domains including an Nโ€