✦ LIBER ✦

Tyrosinase subcellular distribution and kinetic parameters in wild type andc-locus mutant C57BL/6J mice

✍ Scribed by Townsend, Dewayne ;Witkop, Carl J. ;Mattson, Judith

Publisher: John Wiley and Sons
Year: 1981
Tongue: English
Weight: 572 KB
Volume: 216
Category: Article
ISSN: 0022-104X
DOI: 10.1002/jez.1402160112

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✦ Synopsis

Abstract

The distribution and kinetic parameters of tyrosinase (EC 1.14.–18.1) from anagen hair follicles of the C57BL/6J mouse and several c‐locus mutants were investigated. The results showed that c‐locus mutations not only influenced the total tyrosinase activity, but the subcellular distribution as well. The kinetic parameters of tyrosinase were not influenced by the pigment mutations, suggesting that the mutations were not influencing the structure of the enzyme.

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