Tyrosinase-mediated in situ forming hydrogels from biodegradable chondroitin sulfate–tyramine conjugates

Enzyme-mediated fast in situ formation o

Enzyme-mediated fast in situ formation of hydrogels from dextran–tyramine conjugates

✍ Rong Jin; Christine Hiemstra; Zhiyuan Zhong; Jan Feijen 📂 Article 📅 2007 🏛 Elsevier Science 🌐 English ⚖ 317 KB

Dextran hydrogels were formed in situ by enzymatic crosslinking of dextran-tyramine conjugates and their mechanical, swelling and degradation properties were evaluated. Two types of dextran-tyramine conjugates (M n,dextran ¼ 14 k, M w /M n ¼ 1.45), i.e. dextran-tyramine linked by a urethane bond (de