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Tyrosinase inhibitory activity of proanthocyanidins from woody plants

โœ Scribed by Keiji Takagi; Tohru Mitsunaga


Publisher
Springer
Year
2003
Tongue
English
Weight
224 KB
Volume
49
Category
Article
ISSN
1435-0211

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Synthesis and tyrosinase inhibitory acti
โœ Mitsuhiro Shiino; Yumi Watanabe; Kazuo Umezawa ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 137 KB

Several novel N-substituted N-nitrosohydroxylamines were synthesized. They all inhibited mushroom tyrosinase, but the type of inhibition was different depending on the substituent. Some N-(mono- or dihydroxybenzyl)-N-nitrosohydroxylamines exhibited uncompetitive inhibition with respect to L-dopa. Am