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Tyrosinase exacerbates dopamine toxicity but is not genetically associated with Parkinson's disease

✍ Scribed by Elisa Greggio; Elisabetta Bergantino; Donald Carter; Rili Ahmad; Gertrude-Emilia Costin; Vincent J. Hearing; Jordi Clarimon; Andrew Singleton; Johanna Eerola; Olli Hellström; Pentti J. Tienari; David W. Miller; Alexandra Beilina; Luigi Bubacco; Mark R. Cookson

Book ID
111178797
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
267 KB
Volume
93
Category
Article
ISSN
0022-3042

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✍ B. Jasinska-Myga; C. Wider; G. Opala; A. Krygowska-Wajs; M. Barcikowska; K. Czyz 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 74 KB

**Background and purpose:** A single nucleotide polymorphism in the 3′‐untranslated region of the progranulin gene (__GRN__; 3′UTR+78C>T; rs5848) was reported to alter the risk for frontotemporal lobar degeneration with ubiquitin‐positive inclusions (FTLD‐U). rs5848 is located within a micro‐RNA bin