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Tyr1and Ile7of glucose-dependent insulinotropic polypeptide (GIP) confer differential ligand selectivity toward GIP and glucagon-like peptide-1 receptors

✍ Scribed by Mi Jin Moon; Hee Young Kim; Sin Gon Kim; Juri Park; Dong Seop Choi; Jong-Ik Hwang; Jae Young Seong


Book ID
106263096
Publisher
Korean Society for Molecular and Cellular Biology
Year
2010
Tongue
English
Weight
465 KB
Volume
30
Category
Article
ISSN
1016-8478

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## Background: The insulinotropic hormones, glucose-dependent insulinotropic polypeptide (gip) and glucagon-like peptide-1 (7-36 amide) (glp-1), regulate insulin secretion to nutrient intake and constitute the endocrine arm of the entero-insular axis. glucagon has been implicated in the pathophysio