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Typing of HLA class II and class I antigens using PHA-activated, IL-2-propagated T lymphocytes

✍ Scribed by B. Leshem; I. Cohen; L. Sherman; C. Brautbar; E. Kedar


Book ID
118901003
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
361 KB
Volume
111
Category
Article
ISSN
0022-1759

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✍ Kohichi Sakamoto; Hiroto Nakajima; Jun Shimizu; Tatsuo Katagiri; Chiharu Kiyotak πŸ“‚ Article πŸ“… 1988 πŸ› Springer-Verlag 🌐 English βš– 660 KB

The present study investigated the role of antigen-presenting cells (APC) in the activation of noncytolytic T cells against tumor antigens. The noncytolytic-type T cells exerted their antitumor effect by producing gamma-interferon (IFN-gamma) and by activating macrophages as the ultimate effectors.