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Type IV Collagen, Type IV Collagenase Activity and Ability of Cell Proliferation in Human Thyroid Tumours

✍ Scribed by Takeshi Kusunoki; Shozo Nishida; Saori Kimoto-Kinoshita; Kiyotaka Murata; Takao Satou; Takanori Tomura

Book ID
114339194
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
102 KB
Volume
25
Category
Article
ISSN
0219-3108

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Monoclonal antibodies (MAbs) against human type-IV collagenase were developed and used for studies on enzyme activity and tumor-cell invasion in vitro. Fifteen MAb clones were generated against the enzyme purified from serum-free culture medium of human melanoma cells (A2058). Five clones affecting