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Type I Interferon Modulates Monocyte Recruitment and Maturation in Chronic Inflammation

✍ Scribed by Pui Y. Lee; Yi Li; Yutaro Kumagai; Yuan Xu; Jason S. Weinstein; Erinn S. Kellner; Dina C. Nacionales; Edward J. Butfiloski; Nico van Rooijen; Shizuo Akira; Eric S. Sobel; Minoru Satoh; Westley H. Reeves

Book ID
117970995
Publisher
American Society for Investigative Pathology
Year
2009
Tongue
English
Weight
1012 KB
Volume
175
Category
Article
ISSN
0002-9440

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## Abstract ## Background The development of dendritic cell (DC)‐based vaccines using antigen‐encoding mRNA requires identification of the critical parameters for efficient __ex vivo__ loading of DCs. Exogenously delivered mRNA can induce DC activation, but the molecular mechanisms involved are un