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Type 2 diabetes – a matter of failing β-cell neogenesis? Clues from the GK rat model

✍ Scribed by J. Movassat; S. Calderari; E. Fernández; M. A. Martín; F. Escrivá; C. Plachot; M. N. Gangnerau; P. Serradas; C. Álvarez; B. Portha

Book ID
109044561
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
352 KB
Volume
9
Category
Article
ISSN
1462-8902

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✍ Bernard Portha 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 195 KB

Now that the reduction in β-mass has been clearly established in humans with type 2 diabetes mellitus (T2DM) [1][2][3][4], the debate focuses on the possible mechanisms responsible for decreased β-cell number and impaired β-cell function and their multifactorial etiology. Appropriate inbred rodent m