It has been very tempting to accept the suggestion that the route to rejection or tolerance of organ transplants is determined by T-helper type 1 and type 2 cells, respectively. Much of the data used to support this idea, however, is indirect and therefore cannot be used to imply a causal role for e
Type 2 cytokines and negative immune regulation in human infections
β Scribed by Robert L. Modlin; Thomas B. Nutman
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 934 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0952-7915
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
CD4 + and CD8 + T cells can be divided based on the cytokines that they secrete into type 1 (Th1, Tc1) and type 2 (Th2, Tc2) subsets. Schistosoma mansoni infection in mice is characterized by a type 2-dominated response. We have used intracellular cytokine staining to demonstrate dramatic changes in
## Abstract The natural history of human Tβlymphotropic virus type I (HTLVβI) has been shown to differ markedly by geographic area. The differences include contrasting patterns of risk of adult Tβcell lymphoma (ATL) and HTLVβIβassociated myelopathy/tropical spastic paraparesis (HAM/TSP), which may
Spermidine/spermine N 1 -acetyltransferase (cSAT), a key enzyme in polyamine degradation, is induced by various hepatotoxins and liver tumor promoters. In this paper we demonstrate that physiological factors, such as cytokines, control cSAT expression in HepG2 human hepatocarcinoma cells. Hepatocyte