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Type 2 A (group II) von Willebrand disease mutations increase the susceptibility of VWF to ADAMTS-13

✍ Scribed by H.-M. Tsai


Book ID
109148609
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
71 KB
Volume
2
Category
Article
ISSN
1538-7933

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## Abstract Most of type 2A von Willebrand disease (VWD) mutations are clustered within the A2 domain of VWF, encoded by the 3β€² region of exon 28 of the von Willebrand factor (VWF) gene. A patient with lifelong and severe bleeding diathesis and laboratory data of type 2A VWD is described. The analy