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Type 1 vs type 2 calreticulin mutations in primary myelofibrosis: differences in phenotype and prognostic impact

✍ Scribed by Tefferi, A. (author);Lasho, T. L. (author);Finke, C. (author);Belachew, A. A. (author);Wassie, E. A. (author);Ketterling, R. P. (author);Hanson, C. A. (author);Pardanani, A. (author)

Book ID
121649584
Publisher
Nature Publishing Group
Year
2014
Tongue
English
Weight
180 KB
Volume
28
Category
Article
ISSN
0887-6924

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Previous studies have shown that certain strains of herpes simplex viruses type 1 (HSV-1) are able to induce "fusion from without" (FFWO) which means no transcription or translation of the viral genome happens. The main determinants for FFWO in BHK cells are mutations in the C-terminal part of gB-1.